BROTHER AGAINST BROTHER! Miguel O'Hara is completely out of control. The symbiote is taking over. Kron Stone, A.K.A. VENOM 2099, has pushed them both over the edge. Is Miguel willing to trade the lives of his friends and family, the years of good he did as SPIDER-MAN - all for unrivaled power?! All of Nueva York will be Spidey and Venom's battlefield for this climactic conclusion!